Institution/Agency: Rush University Medical Center – Chicago, Illinois
Principal Investigator: Debra E Weese-Mayer, MD
Dates Funded: November 2001 – February 2008
Project: Polymorphisms and Mutations in Genes that May Contribute to SIDS Risk
Description: Dr. Weese-Mayer’s research project is to compare genotype and allele frequencies for functional polymorphisms in key serotonergic genes that function as early and precise markers of serotonin neurons, or that play a role in serotonin neuronal function or serotonin transporter gene function. The long term goal is to define the genetic profile for the infant at heightened risk for SIDS.
Research Publications List
- Maher BS, Marazita ML, Rand C, Zhou L, Berry-Kravis EM, Weese-Mayer DE. 2006. 30 UTR polymorphism of thenserotonin transporter gene and sudden infant death syndrome: Haplotype analysis. Am J Med Genet Part A1 40A:1453–1457.
- Debra E. Weese-Mayer, Michael J. Ackerman, Mary L. Marazita, and Elizabeth M. Berry-Kravis, Research Review Sudden Infant Death Syndrome: Review of Implicated Genetic Factors American Journal of Medical Genetics Part A 143A:771–788 (2007)
- Casey M. Rand, Debra E. Weese-Mayer, Brion S. Maher, Lili Zhou, Mary L. Marazita, and Elizabeth M. Berry-Kravis, Nicotine Metabolizing Genes GSTT1 and CYP1A1 in Sudden Infant Death Syndrome, American Journal of Medical Genetics Part A 140A:1447–1452 (2006